Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 4/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | NEK2 | P51955 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | JAK1 | P23458 | 2/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13800584 | 1.00 | HTR7 (0.43) | HTR7DRD4DRD2DRD3HCRTR1 | |
| Hydrochloric Acid SCHEMBL7218593 | 0.99 | HTR7 (0.42) | HTR7DRD4DRD2DRD3HCRTR1 | |
| Hydrochloric Acid SCHEMBL7217824 | 0.99 | HTR7 (0.42) | HTR7DRD4DRD2DRD3HCRTR1 | |
| SCHEMBL13800579 | 0.95 | JAK2 (0.39) | HTR7DRD4DRD2DRD3HCRTR1 | |
| Hydrochloric Acid SCHEMBL7217655 | 0.94 | JAK2 (0.39) | HTR7HCRTR1HCRTR2CHEK1NEK2 | |
| SCHEMBL6166365 | 0.93 | DRD4 (0.45) | HTR7DRD4DRD2DRD3HCRTR1 | |
| SCHEMBL13800336 | 0.93 | DRD4 (0.45) | HTR7DRD4DRD2DRD3HCRTR1 | |
| SCHEMBL13800775 | 0.93 | HTR7 (0.46) | HTR7DRD4DRD2DRD3HCRTR1 | |
| SCHEMBL13800660 | 0.93 | MCL1 (0.43) | HTR7DRD4DRD2DRD3HCRTR1 | |
| SCHEMBL13800742 | 0.93 | HTR7 (0.44) | HTR7DRD4DRD2DRD3HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143430-A1 | ERYTHROPOIETIN PRODUCTION ACCELERATOR | KOWA CO., LTD. (JP) | 2009-06-04 | — | — | US | disclosed |
| US-20090143430-A1 | ERYTHROPOIETIN PRODUCTION ACCELERATOR | KOWA CO., LTD. (JP) | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143430-A1 | ERYTHROPOIETIN PRODUCTION ACCELERATOR | EPOR, GHRHR, ARL1 | HTR7 3747/4885DRD4 1352/4885DRD2 2405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.