Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | LDHB | P07195 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1379885 | 0.89 | F10 (0.56) | F10 | |
| SCHEMBL1376448 | 0.87 | RAB9A (0.52) | F10L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL1377310 | 0.86 | F10 (0.61) | F10L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL15546651 | 0.85 | F10 (0.54) | F10L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL1380603 | 0.83 | F10 (0.59) | F10 | |
| SCHEMBL5629061 | 0.80 | F10 (0.54) | F10L3MBTL1 | |
| SCHEMBL5629077 | 0.80 | F10 (0.56) | F10 | |
| SCHEMBL5628607 | 0.80 | F10 (0.54) | F10L3MBTL1 | |
| SCHEMBL5628624 | 0.80 | F10 (0.56) | F10 | |
| SCHEMBL5625557 | 0.80 | F10 (0.55) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4732757-B2 | — | — | 2011-07-27 | — | — | JP | claimed |
| JP-2006512321-A | — | — | 2006-04-13 | — | — | JP | claimed |
| EP-1562939-A1 | CARBOXAMIDES | MERCK PATENT GmbH (DE) | 2005-08-17 | — | — | EP | claimed |
| WO-2004046138-A1 | CARBOXAMIDES | MERCK PATENT GMBH (DE) | 2004-06-03 | — | — | WO | claimed |
| EP-1562939-A1 | CARBOXAMIDES | MERCK PATENT GmbH (DE) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004046138-A1 | CARBOXAMIDES | MERCK PATENT GMBH (DE) | 2004-06-03 | — | — | WO | disclosed |