Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 4/20 | 0.51 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5873331 | 0.88 | F10 (0.55) | RAB9ANPC1TP53TSHRF10 | |
| SCHEMBL1380098 | 0.87 | F10 (0.53) | RAB9ANPC1F10L3MBTL1MAPT | |
| SCHEMBL1377310 | 0.87 | F10 (0.61) | RAB9ANPC1F10L3MBTL1KDM4E | |
| SCHEMBL15546651 | 0.86 | F10 (0.54) | RAB9ANPC1F10L3MBTL1MAPT | |
| SCHEMBL6181035 | 0.82 | F10 (0.60) | RAB9ANPC1TP53TSHRF10 | |
| SCHEMBL1378537 | 0.80 | F10 (0.53) | F10 | |
| SCHEMBL8315691 | 0.80 | F10 (0.54) | RAB9ANPC1TP53TSHRF10 | |
| SCHEMBL1377268 | 0.79 | F10 (0.55) | TSHRF10 | |
| SCHEMBL5625645 | 0.78 | F10 (0.56) | F10KDM4E | |
| SCHEMBL5624652 | 0.78 | F10 (0.56) | F10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4732757-B2 | — | — | 2011-07-27 | — | — | JP | claimed |
| JP-2006512321-A | — | — | 2006-04-13 | — | — | JP | claimed |
| EP-1562939-A1 | CARBOXAMIDES | MERCK PATENT GmbH (DE) | 2005-08-17 | — | — | EP | claimed |
| WO-2004046138-A1 | CARBOXAMIDES | MERCK PATENT GMBH (DE) | 2004-06-03 | — | — | WO | claimed |