Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HMGCR | P04035 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 3/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | PGK2 | P07205 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.35 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15705739 | 0.87 | HMGCR (0.52) | POLBHMGCRMEN1KMT2AGAA | |
| SCHEMBL8990147 | 0.84 | MAPT (0.44) | POLBHMGCRESR1ESR2PGK1 | |
| SCHEMBL9549401 | 0.84 | PPARD (0.41) | POLBHMGCRESR1ESR2PGK1 | |
| SCHEMBL18383706 | 0.82 | POLB (0.39) | POLBHMGCRPGK1PGK2PTGS2 | |
| SCHEMBL1459085 | 0.81 | POLB (0.36) | POLBHMGCRESR1MEN1KMT2A | |
| SCHEMBL15101340 | 0.80 | MAPT (0.38) | POLBHMGCRESR1ESR2PGK1 | |
| SCHEMBL4212110 | 0.79 | THRA (0.48) | POLBESR1ESR2HDAC1CA1 | |
| SCHEMBL12660721 | 0.79 | HMGCR (0.61) | POLBHMGCRMEN1KMT2AGAA | |
| SCHEMBL11300456 | 0.76 | HMGCR (0.39) | POLBHMGCRHDAC1NR1I2 | |
| SCHEMBL4212156 | 0.74 | THRA (0.46) | POLBESR1ESR2HDAC1THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163621-A1 | Process for improving color of polycondensates | SIMON DIRK | 2009-06-25 | — | — | US | disclosed |