Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HMGCR | P04035 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | PGK2 | P07205 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.36 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15101340 | 0.92 | MAPT (0.38) | MAPTHTTEGFRTSHRPPARD | |
| SCHEMBL9549401 | 0.86 | PPARD (0.41) | MAPTPPARDPOLBHMGCRESR1 | |
| SCHEMBL13801014 | 0.84 | POLB (0.37) | MAPTHTTPOLBHMGCRESR1 | |
| SCHEMBL10988240 | 0.83 | ESR1 (0.49) | ESR1 | |
| SCHEMBL13913134 | 0.82 | TSHR (0.50) | MAPTHTTEGFRTSHRPPARD | |
| SCHEMBL282193 | 0.82 | MAPT (0.41) | MAPTHTTEGFRTSHRPPARD | |
| SCHEMBL3396258 | 0.81 | EGFR (0.43) | MAPTHTTEGFRTSHRPPARD | |
| SCHEMBL9464672 | 0.81 | PGK1 (0.38) | ESR1ESR2PGK1PGK2PTGS1 | |
| SCHEMBL27584794 | 0.79 | AKR1B1 (0.41) | MAPTHTTEGFRPOLBGAA | |
| SCHEMBL20971749 | 0.79 | MAPT (0.41) | MAPTHTTEGFRTSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070051403-A1 | Photoelectric Converter and Dye Sensitized Solar Cell | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2007-03-08 | — | — | US | disclosed |
| CN-1489596-A | Alpha-substituted beta-aminoethylphosphonates | �Ʒ� | 2004-04-14 | — | — | CN | disclosed |
| EP-0507738-B1 | Process for preparing sterically mindered hydroxybenzylphosphonates | CIBA GEIGY AG (CH) | 1996-07-17 | — | — | EP | disclosed |
| EP-0434606-B1 | Hydroxybenzylphosphonates and their preparation process | CIBA GEIGY AG (CH) | 1995-08-16 | — | — | EP | disclosed |
| US-5258540-A | Compounds for photostability, heat resistance and oxidation resistance | CIBA-GEIGY CORPORATION (US) | 1993-11-02 | — | — | US | disclosed |
| US-5171873-A | PROCESS FOR THE PREPARATION OF STERICALLY HINDERED HYDROXYBENZYLPHOSPHONATES | CIBA-GEIGY CORPORATION (US) | 1992-12-15 | — | — | US | disclosed |
| US-5157141-A | Reacting phenol derivatives, formaldehyde or parafomaldehyde, an amine and phosphite | CIBA-GEIGY CORPORATION (US) | 1992-10-20 | — | — | US | disclosed |
| EP-0507738-A2 | Process for preparing sterically mindered hydroxybenzylphosphonates | CIBA-GEIGY AG (CH) | 1992-10-07 | — | — | EP | disclosed |
| EP-0434606-A1 | Hydroxybenzylphosphonates and their preparation process | CIBA-GEIGY AG (CH) | 1991-06-26 | — | — | EP | disclosed |