Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 8/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17922219 | 0.93 | ALDH1A1 (0.56) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL14015781 | 0.90 | THRB (0.57) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL27055881 | 0.89 | THRB (0.55) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL27055871 | 0.89 | THRB (0.55) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL27055888 | 0.89 | THRB (0.55) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL13917109 | 0.89 | THRB (0.55) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL27055864 | 0.89 | THRB (0.55) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL27055873 | 0.89 | THRB (0.55) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL6742403 | 0.89 | THRB (0.64) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL17922218 | 0.89 | ALDH1A1 (0.71) | THRBALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017195428-A1 | NOVEL COMPOUND, PHOTOCURABLE COMPOSITION, CURED PRODUCT THEREOF, PRINTING INK, AND PRINTED MATTER USING PRINTING INK | DIC株式会社 | 2017-11-16 | — | — | WO | disclosed |
| US-8653214-B2 | Silicone (meth)acrylate particles, process for preparation thereof and use thereof | EVONIK GOLDSCHMIDT GMBH (DE) | 2014-02-18 | — | — | US | disclosed |
| US-20090149573-A1 | SILICONE (METH)ACRYLATE PARTICLES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF | EVONIK GOLDSCHMIDT GMBH (DE) | 2009-06-11 | — | — | US | disclosed |