Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1268643 | 0.94 | ALDH1A1 (0.41) | ALDH1A1LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL13801205 | 0.87 | SMN1; SMN2 (0.40) | ALDH1A1LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL13801201 | 0.86 | ALDH1A1 (0.38) | ALDH1A1LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL13801419 | 0.85 | MERTK (0.39) | ALDH1A1LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL13801420 | 0.85 | ALDH1A1 (0.39) | ALDH1A1LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL13801186 | 0.83 | PDE5A (0.39) | ALDH1A1LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL1270163 | 0.83 | ALDH1A1 (0.41) | ALDH1A1LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL1269394 | 0.82 | ALDH1A1 (0.42) | ALDH1A1LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL12931024 | 0.81 | ALDH1A1 (0.37) | ALDH1A1LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL1268843 | 0.80 | MAPT (0.41) | ALDH1A1LMNAMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544702-B2 | Bisaryl-sulfonamides | AMGEN INC. (US) | 2009-06-09 | — | — | US | disclosed |