Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | PDE5A | O76074 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13801419 | 0.95 | MERTK (0.39) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1269423 | 0.94 | ALDH1A1 (0.39) | ALDH1A1LMNAMEN1KMT2APDE5A | |
| SCHEMBL12931024 | 0.92 | ALDH1A1 (0.37) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13801186 | 0.91 | PDE5A (0.39) | ALDH1A1LMNAMEN1KMT2APDE5A | |
| SCHEMBL1269635 | 0.90 | ALDH1A1 (0.42) | ALDH1A1LMNAMEN1KMT2APDE5A | |
| SCHEMBL1269882 | 0.89 | PTGDR (0.42) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1268550 | 0.87 | ALDH1A1 (0.40) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13801205 | 0.87 | SMN1; SMN2 (0.40) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13790967 | 0.86 | L3MBTL1 (0.41) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13801185 | 0.86 | ALDH1A1 (0.40) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544702-B2 | Bisaryl-sulfonamides | AMGEN INC. (US) | 2009-06-09 | — | — | US | disclosed |