Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 19/20 | 0.65 |
| ▸ | KCNA5 | P22460 | 14/20 | 0.65 |
| ▸ | KCNA4 | P22459 | 2/20 | 0.65 |
| ▸ | KCNA1 | Q09470 | 2/20 | 0.65 |
| ▸ | KCNA2 | P16389 | 2/20 | 0.65 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | KCNA6 | P17658 | 1/20 | 0.65 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.65 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.65 |
| ▸ | KCNA7 | Q96RP8 | 1/20 | 0.65 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11471104 | 0.88 | KCNA3 (0.64) | KCNA3KCNA5KCNA4KCNA1KCNA2 | |
| Hydrochloric Acid SCHEMBL11473139 | 0.86 | KCNA3 (0.62) | KCNA3KCNA5KCNA4KCNA1KCNA2 | |
| SCHEMBL23406793 | 0.83 | KCNA3 (0.69) | KCNA3KCNA5KCNA4KCNA1KCNA2 | |
| SCHEMBL9122678 | 0.82 | ALDH1A1 (0.71) | KCNA3KCNA5KCNA4KCNA1KCNA2 | |
| SCHEMBL29503682 | 0.82 | KCNA3 (0.71) | KCNA3KCNA5KCNA4KCNA1KCNA2 | |
| SCHEMBL7754086 | 0.82 | KCNA3 (0.71) | KCNA3KCNA5KCNA4KCNA1KCNA2 | |
| SCHEMBL2586445 | 0.82 | KCNA3 (0.76) | KCNA3KCNA5KCNA4KCNA1KCNA2 | |
| SCHEMBL25981033 | 0.81 | CYP2D6 (0.68) | KCNA3KCNA5KCNA4KCNA1KCNA2 | |
| SCHEMBL4123742 | 0.80 | KCNA3 (0.68) | KCNA3KCNA5KCNA4KCNA1KCNA2 | |
| SCHEMBL2587752 | 0.79 | KCNA3 (1.00) | KCNA3KCNA5KCNA4KCNA1KCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8071642-B2 | Dimethyl amino ethyl ether psoralens and methods for their production and use | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2011-12-06 | — | — | US | disclosed |
| US-20090155224-A1 | Dimethyl amino ethyl ether psoralens and methods for their production and use | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090155224-A1 | Dimethyl amino ethyl ether psoralens and methods for their production and use | HLA-C, HLA-A, HLA-B | KCNA3 4600/4885KCNA5 4697/4885KCNA4 4652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.