Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 3/20 | 0.46 |
| ▸ | RAMP1 | O60894 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 9/20 | 0.37 |
| ▸ | DRD2 | P14416 | 8/20 | 0.37 |
| ▸ | DRD3 | P35462 | 7/20 | 0.37 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 4/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12400695 | 0.85 | CALCRL (0.47) | CALCRLRAMP1CTSSDRD4DRD2 | |
| SCHEMBL13907972 | 0.85 | CALCRL (0.47) | CALCRLRAMP1CTSSDRD4DRD2 | |
| SCHEMBL13313602 | 0.85 | CALCRL (0.47) | CALCRLRAMP1CTSSDRD4DRD2 | |
| SCHEMBL12219072 | 0.83 | HPGD (0.46) | CALCRLRAMP1CTSSNSD3CNR1 | |
| SCHEMBL3278017 | 0.83 | CALCRL (0.55) | CALCRLRAMP1CTSSCNR1GPR55 | |
| SCHEMBL3278151 | 0.82 | CALCRL (0.44) | CALCRLRAMP1CTSSDRD4DRD2 | |
| SCHEMBL2257145 | 0.82 | NSD3 (0.53) | CALCRLRAMP1CTSSNSD3BTK | |
| SCHEMBL404497 | 0.82 | CALCRL (0.45) | CALCRLRAMP1CTSSDRD4DRD2 | |
| SCHEMBL439501 | 0.82 | CALCRL (0.45) | CALCRLRAMP1CTSSDRD4DRD2 | |
| SCHEMBL4079747 | 0.80 | CALCRL (0.48) | CALCRLRAMP1CTSSDRD4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | DR. KARL THOMAE GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | DR. KARL THOMAE GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
| US-7498325-B2 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | KARL THOMAS GMBH (DE) | 2009-03-03 | — | — | US | disclosed |
| US-7498325-B2 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | KARL THOMAS GMBH (DE) | 2009-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | PTMS, CHRM1, SRMS | CALCRL 255/4885RAMP1 354/4885CTSS 2562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.