Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 16/20 | 0.57 |
| ▸ | TACR2 | P21452 | 2/20 | 0.42 |
| ▸ | PTGES | O14684 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13801575 | 0.88 | TRPV1 (0.61) | TRPV1PTGESALOX5 | |
| SCHEMBL13801580 | 0.88 | TRPV1 (0.70) | TRPV1PTGESALOX5 | |
| SCHEMBL3117663 | 0.87 | TRPV1 (0.51) | TRPV1TACR2 | |
| SCHEMBL13801576 | 0.87 | TRPV1 (0.70) | TRPV1 | |
| SCHEMBL13801573 | 0.84 | TRPV1 (0.70) | TRPV1TACR2PTGESALOX5 | |
| SCHEMBL4159118 | 0.79 | TRPV1 (0.50) | TRPV1TACR2 | |
| SCHEMBL3115787 | 0.78 | TRPV1 (0.61) | TRPV1 | |
| SCHEMBL13801579 | 0.78 | TRPV1 (0.70) | TRPV1PTGESALOX5 | |
| SCHEMBL13801561 | 0.77 | TRPV1 (0.53) | TRPV1PTGESALOX5 | |
| SCHEMBL13801578 | 0.77 | TRPV1 (0.68) | TRPV1PTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156598-A1 | Imidazolopyrimidine modulators of TRPV1 | JANSSEN PHARMACEUTICA NV (BE) | 2009-06-18 | — | — | US | disclosed |
| US-20090156598-A1 | Imidazolopyrimidine modulators of TRPV1 | JANSSEN PHARMACEUTICA NV (BE) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156598-A1 | Imidazolopyrimidine modulators of TRPV1 | TRPV1, TRPV2, TRPV5 | TRPV1 1/4885TACR2 1679/4885PTGES 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.