Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 5/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.44 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.43 |
| ▸ | TACR2 | P21452 | 4/20 | 0.42 |
| ▸ | TAC3 | Q9UHF0 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4144176 | 0.99 | SLC6A2 (0.45) | TACR1SLC6A2SLC6A4SLC6A3SSTR1 | |
| Hydrochloric Acid SCHEMBL4144170 | 0.99 | SLC6A2 (0.45) | TACR1SLC6A2SLC6A4SLC6A3SSTR1 | |
| SCHEMBL4153751 | 0.83 | TACR2 (0.61) | TACR1SLC6A2SLC6A4SLC6A3TACR2 | |
| Hydrochloric Acid SCHEMBL4141232 | 0.82 | TACR1 (0.60) | TACR1SLC6A2SLC6A4SLC6A3TACR2 | |
| Hydrochloric Acid SCHEMBL4141228 | 0.82 | TACR1 (0.60) | TACR1SLC6A2SLC6A4SLC6A3TACR2 | |
| Hydrochloric Acid SCHEMBL4141381 | 0.82 | TACR2 (0.60) | TACR1SLC6A2SLC6A4SLC6A3TACR2 | |
| Hydrochloric Acid SCHEMBL4149798 | 0.82 | TACR1 (0.60) | TACR1SLC6A2SLC6A4SLC6A3TACR2 | |
| Hydrochloric Acid SCHEMBL4149374 | 0.82 | TACR1 (0.60) | TACR1SLC6A2SLC6A4SLC6A3TACR2 | |
| SCHEMBL4144959 | 0.81 | TACR2 (0.49) | TACR1SLC6A2SLC6A4SLC6A3TACR2 | |
| SCHEMBL4144966 | 0.81 | TACR2 (0.49) | TACR1SLC6A2SLC6A4SLC6A3TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470816-B2 | Nitrogen-containing heterocyclic compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-06-25 | — | — | US | disclosed |
| US-20090156572-A1 | Nitrogen-containing heterocyclic compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2009-06-18 | — | — | US | disclosed |
| US-20090156572-A1 | Nitrogen-containing heterocyclic compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156572-A1 | Nitrogen-containing heterocyclic compound and use thereof | NTSR2, NTSR1, HNMT | TACR1 9/4885SLC6A2 241/4885SLC6A4 271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.