Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27849930 | 0.90 | GAA (0.62) | KDM4EGAAMAPTLMNAALOX12 | |
| SCHEMBL14857780 | 0.87 | KDM4E (0.50) | KDM4EGAAMAPTLMNAALOX12 | |
| SCHEMBL15928746 | 0.85 | GAA (0.66) | KDM4EGAAMAPTLMNAALOX12 | |
| SCHEMBL11523761 | 0.82 | KDM4E (0.73) | KDM4EGAAMAPTLMNAIDO1 | |
| SCHEMBL29449726 | 0.82 | KDM4E (0.73) | KDM4EGAAMAPTLMNAIDO1 | |
| SCHEMBL20336230 | 0.82 | KDM4E (0.73) | KDM4EGAAMAPTLMNAIDO1 | |
| SCHEMBL4495740 | 0.82 | KDM4E (0.73) | KDM4EGAAMAPTLMNAIDO1 | |
| SCHEMBL23016004 | 0.82 | GAA (0.61) | KDM4EGAAMAPTLMNAALOX12 | |
| SCHEMBL7634561 | 0.82 | GAA (0.61) | KDM4EGAAMAPTLMNAALOX12 | |
| SCHEMBL5981593 | 0.81 | IDO1 (0.46) | KDM4EGAAMAPTLMNAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114105783-A | Anti-aging agent and preparation method thereof | 王兴路 | 2022-03-01 | — | — | CN | disclosed |
| EP-2245123-B1 | METHODS FOR PRODUCING ALKYLATED 1,3 BENZENEDIAMINE COMPOUNDS | CHEMTURA CORP (US) | 2017-07-19 | — | — | EP | disclosed |
| WO-2009076091-A2 | ALKYLATED 1,3 BENZENEDIAMINE COMPOUNDS AND METHODS FOR PRODUCING SAME | CHEMTURA CORPORATION (US) | 2009-06-18 | — | — | WO | disclosed |