Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13801654 | 0.85 | KDM4E (0.58) | GAAMAPTKDM4ETSHRLMNA | |
| SCHEMBL2933468 | 0.81 | KDM4E (0.96) | GAAMAPTKDM4ELMNAALOX15 | |
| SCHEMBL31069575 | 0.81 | KDM4E (0.96) | GAAMAPTKDM4ELMNAALOX15 | |
| SCHEMBL27849930 | 0.80 | GAA (0.62) | GAAMAPTKDM4ETSHRLMNA | |
| SCHEMBL23016005 | 0.79 | KDM4E (1.00) | GAAMAPTKDM4ELMNAALOX15 | |
| SCHEMBL17874938 | 0.79 | KDM4E (1.00) | GAAMAPTKDM4ELMNAALOX15 | |
| SCHEMBL5450859 | 0.79 | KDM4E (1.00) | GAAMAPTKDM4ELMNAALOX15 | |
| SCHEMBL29922301 | 0.79 | KDM4E (1.00) | GAAMAPTKDM4ELMNAALOX15 | |
| SCHEMBL541824 | 0.79 | KDM4E (1.00) | GAAMAPTKDM4ELMNAALOX15 | |
| SCHEMBL14857780 | 0.77 | KDM4E (0.50) | GAAMAPTKDM4ETSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014118092-A2 | DYE COMPOSITION COMPRISING AT LEAST ONE PARTICULAR LIPOPHILIC META-PHENYLENEDIAMINE COUPLER IN A MEDIUM RICH IN FATTY SUBSTANCES, PROCESSES AND DEVICES | L'OREAL (FR) | 2014-08-07 | — | — | WO | disclosed |