Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.42 |
| ▸ | TYMP | P19971 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573049 | 1.00 | PNP (0.50) | PNPALDH1A1LMNAALBMAPK1 | |
| SCHEMBL4250337 | 1.00 | PNP (0.50) | PNPALDH1A1LMNAALBMAPK1 | |
| SCHEMBL13813965 | 1.00 | PNP (0.50) | PNPALDH1A1LMNAALBMAPK1 | |
| SCHEMBL1573051 | 0.76 | AHCY (0.38) | ADORA3 | |
| SCHEMBL9310418 | 0.76 | ALDH1A1 (0.58) | PNPALDH1A1LMNAALBMAPK1 | |
| SCHEMBL4250330 | 0.76 | AHCY (0.38) | ADORA3 | |
| SCHEMBL10395086 | 0.73 | ALDH1A1 (0.55) | PNPALDH1A1LMNAALBMAPK1 | |
| SCHEMBL9308280 | 0.73 | ALDH1A1 (0.60) | PNPALDH1A1LMNAALBMAPK1 | |
| SCHEMBL12715510 | 0.72 | HPRT1 (0.38) | PNPALDH1A1LMNAALBMAPK1 | |
| SCHEMBL13801674 | 0.71 | HPRT1 (0.42) | LMNAHPRT1TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553839-B2 | 5h-pyrrolo[3,2-D] pyrimidine inhibitors of nucleoside phosphorylases and nucleosidases | INDUSTRIAL RESEARCH LIMITED (NZ) | 2009-06-30 | — | — | US | disclosed |