Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 9/20 | 0.74 |
| ▸ | NAMPT | P43490 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13801795 | 0.96 | KISS1R (0.68) | KISS1RNAMPT | |
| SCHEMBL13801738 | 0.93 | KISS1R (0.62) | KISS1RNAMPT | |
| SCHEMBL13801849 | 0.92 | KISS1R (0.60) | KISS1RNAMPT | |
| SCHEMBL13801773 | 0.91 | KISS1R (0.60) | KISS1RNAMPT | |
| SCHEMBL13801784 | 0.90 | KISS1R (0.75) | KISS1RNAMPT | |
| SCHEMBL13801762 | 0.89 | MEN1 (0.61) | KISS1RNAMPT | |
| SCHEMBL13801750 | 0.86 | KISS1R (0.59) | KISS1RNAMPTALDH1A1 | |
| SCHEMBL13801895 | 0.86 | KISS1R (0.54) | KISS1RNAMPT | |
| SCHEMBL13801799 | 0.85 | KISS1R (1.00) | KISS1R | |
| SCHEMBL13801882 | 0.85 | KISS1R (0.74) | KISS1RTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156646-A1 | PYRIDYLPHENOL COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
| US-20090156646-A1 | PYRIDYLPHENOL COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156646-A1 | PYRIDYLPHENOL COMPOUND AND USE THEREOF | GNRHR, PGR, MC1R | KISS1R 16/4885NAMPT 947/4885ALDH1A1 3446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.