Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.83 |
| ▸ | NPC1 | O15118 | 5/20 | 0.67 |
| ▸ | RAB9A | P51151 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13802101 | 0.88 | ALDH1A1 (0.78) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL13790820 | 0.87 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL3902334 | 0.86 | KMT2A (0.62) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL3903353 | 0.83 | MEN1 (0.57) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL3902355 | 0.79 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL6624465 | 0.79 | ALDH1A1 (0.79) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL14927290 | 0.78 | ALDH1A1 (0.67) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL3903274 | 0.77 | NPC1 (0.71) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7605827 | 0.76 | HTT (0.68) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL1814173 | 0.76 | KCNK3 (0.82) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553867-B2 | Furan or thiophene derivative and medicinal use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-30 | — | — | US | disclosed |