Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.79 |
| ▸ | MEN1 | O00255 | 5/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.79 |
| ▸ | HPGD | P15428 | 4/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.73 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.53 |
| ▸ | NQO2 | P16083 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13791012 | 0.84 | MEN1 (1.00) | ALDH1A1MEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL3913419 | 0.84 | MEN1 (1.00) | ALDH1A1MEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL3913421 | 0.84 | MEN1 (1.00) | ALDH1A1MEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL14927290 | 0.83 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL313244 | 0.82 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL5990487 | 0.81 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL8507040 | 0.80 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL14927266 | 0.80 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL3915795 | 0.80 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL13790820 | 0.80 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AHPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1435934-A1 | 5'-ACYLAMINO-1,1'-BIPHENYL-4-CARBOXAMIDE DERIVATIVES AND THEIR USE AS P38 KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003032971-A1 | 5’-ACYLAMINO-1,1’-BIPHENYL-4-CARBOXAMIDE DERIVATIVES AND THEIR USE AS P38 KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-04-24 | — | — | WO | disclosed |