Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CCR2 | P41597 | 3/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CCR9 | P51686 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6085520 | 0.84 | CCR2 (0.56) | MAPTKDM4EALDH1A1ALOX15CCR2 | |
| SCHEMBL6648744 | 0.83 | PTGS2 (0.53) | MAPTKDM4EALDH1A1ALOX15CCR2 | |
| SCHEMBL16818945 | 0.83 | PTGDR2 (0.49) | MAPTKDM4EALDH1A1ALOX15CCR2 | |
| SCHEMBL4198698 | 0.82 | CCR2 (0.71) | KDM4EALDH1A1CCR2MEN1KMT2A | |
| SCHEMBL27204184 | 0.80 | KDM4E (0.54) | MAPTKDM4EALDH1A1ALOX15CCR2 | |
| SCHEMBL10237658 | 0.80 | CCR2 (0.52) | CCR2PTGDR2PPARGPTGS2 | |
| SCHEMBL9959522 | 0.79 | NPSR1 (0.46) | MAPTKDM4EALDH1A1CCR2PTGDR2 | |
| SCHEMBL6085466 | 0.79 | CCR2 (0.67) | MAPTKDM4EALDH1A1ALOX15CCR2 | |
| SCHEMBL9959557 | 0.79 | PTGS2 (0.64) | MAPTKDM4EALDH1A1ALOX15CCR2 | |
| Acetic Acid SCHEMBL3967081 | 0.79 | CCR2 (0.63) | MAPTALDH1A1CCR2PTGDR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | APP, PSEN2, PSEN1 | MAPT 6/4885KDM4E 4461/4885ALDH1A1 2808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.