Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.76 |
| ▸ | THRA | P10827 | 1/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.66 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.65 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.61 |
| ▸ | PTGES | O14684 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4209387 | 0.91 | PTGDR2 (0.74) | PTGDR2THRATHRBPLA2G2APLA2G1B | |
| SCHEMBL4211522 | 0.90 | PTGDR2 (0.72) | PTGDR2THRATHRBPLA2G2APLA2G1B | |
| SCHEMBL4270126 | 0.87 | THRA (0.71) | PTGDR2THRATHRBPLA2G2APLA2G1B | |
| SCHEMBL13802405 | 0.87 | PTGDR2 (0.70) | PTGDR2THRATHRBPLA2G2APLA2G1B | |
| SCHEMBL13802404 | 0.86 | PTGDR2 (1.00) | PTGDR2THRATHRBPLA2G2APLA2G1B | |
| SCHEMBL4200412 | 0.86 | PTGDR2 (0.69) | PTGDR2THRATHRBPLA2G2APLA2G1B | |
| SCHEMBL13802427 | 0.86 | THRA (0.65) | PTGDR2THRATHRBPLA2G2APLA2G1B | |
| SCHEMBL7963412 | 0.85 | PLA2G2A (0.65) | PTGDR2THRATHRBPLA2G2APLA2G1B | |
| SCHEMBL29941473 | 0.82 | PLA2G2A (0.75) | PTGDR2PLA2G2AGFERALDH1A1KDM4E | |
| SCHEMBL9585168 | 0.82 | PTGDR2 (0.54) | PTGDR2THRATHRBPLA2G2APLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | APP, PSEN2, PSEN1 | PTGDR2 2287/4885THRA 3787/4885THRB 3290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.