Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.71 |
| ▸ | NPC1 | O15118 | 4/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | MITF | O75030 | 1/20 | 0.68 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.67 |
| ▸ | GPR17 | Q13304 | 2/20 | 0.66 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.66 |
| ▸ | THRA | P10827 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | CRHBP | P24387 | 1/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13802453 | 0.87 | MEN1 (0.81) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL7378302 | 0.86 | ALOX5 (0.80) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL10944138 | 0.84 | ALOX5 (0.82) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL3674558 | 0.83 | KCNK3 (0.71) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL1883258 | 0.83 | MEN1 (0.71) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL12639153 | 0.83 | MEN1 (0.71) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL22251590 | 0.83 | MEN1 (0.71) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL3817483 | 0.83 | MEN1 (0.71) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL16441804 | 0.83 | ALOX5 (0.63) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL12834030 | 0.82 | MEN1 (0.64) | MEN1KMT2ANPC1RAB9AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | APP, PSEN2, PSEN1 | MEN1 694/4885KMT2A 2408/4885NPC1 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.