Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CTSV | O60911 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | RXRG | P48443 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1319458 | 0.87 | CTSV (0.63) | MEN1KMT2AALDH1A1CTSVCTSL | |
| SCHEMBL3814086 | 0.85 | PTGER1 (0.64) | ALDH1A1MRGPRX4RXRARXRBRXRG | |
| SCHEMBL1648397 | 0.81 | LRRK2 (0.67) | MRGPRX4RXRARXRBRXRGNR4A2 | |
| SCHEMBL5839822 | 0.80 | KMT2A (0.74) | MEN1KMT2AALDH1A1CTSVCTSL | |
| SCHEMBL1388211 | 0.79 | PTGER1 (0.60) | MEN1KMT2AMRGPRX4RXRARXRB | |
| SCHEMBL28834633 | 0.79 | CYP19A1 (0.56) | MEN1KMT2AALDH1A1CTSVCTSL | |
| SCHEMBL4649097 | 0.78 | MEN1 (0.60) | MEN1KMT2AALDH1A1CTSVCTSL | |
| SCHEMBL1647948 | 0.77 | CYP19A1 (0.64) | MEN1KMT2AALDH1A1CTSVCTSL | |
| SCHEMBL31634197 | 0.77 | MAOB (0.61) | LMNARXRARXRBRXRG | |
| SCHEMBL20581857 | 0.77 | KMT2A (0.58) | MEN1KMT2AALDH1A1CTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | APP, PSEN2, PSEN1 | MEN1 694/4885KMT2A 2408/4885ALDH1A1 2808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.