Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CTSV | O60911 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 2/20 | 0.55 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PPIA | P62937 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1319458 | 0.89 | CTSV (0.63) | MEN1KMT2AMAPTCYP19A1ALDH1A1 | |
| SCHEMBL18153986 | 0.87 | CYP19A1 (0.54) | MEN1KMT2AMAPTCYP19A1ALDH1A1 | |
| SCHEMBL4412940 | 0.87 | MAOB (0.51) | MEN1KMT2AMAPTCYP19A1PKM | |
| SCHEMBL20581857 | 0.86 | KMT2A (0.58) | MEN1KMT2AMAPTCYP19A1ALDH1A1 | |
| SCHEMBL9157553 | 0.86 | MEN1 (0.62) | MEN1KMT2AMAPTCYP19A1ALDH1A1 | |
| SCHEMBL6567396 | 0.85 | MEN1 (0.64) | MEN1KMT2AMAPTCYP19A1ALDH1A1 | |
| SCHEMBL2297894 | 0.84 | MEN1 (0.66) | MEN1KMT2AMAPTCYP19A1ALDH1A1 | |
| SCHEMBL22117864 | 0.83 | MEN1 (0.62) | MEN1KMT2AMAPTCYP19A1ALDH1A1 | |
| SCHEMBL31174832 | 0.83 | MEN1 (0.62) | MEN1KMT2AMAPTCYP19A1ALDH1A1 | |
| SCHEMBL3949981 | 0.83 | MEN1 (0.58) | MEN1KMT2AMAPTCYP19A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963292-A2 | ORGANIC COMPOUNDS | Novartis Pharma AG (CH) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007067615-A2 | THIADIAZOLE DERIVATIVES AS ANTIDIABETIC AGENTS | NOVARTIS AG (CH) | 2007-06-14 | — | — | WO | disclosed |