Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | PLA2G10 | O15496 | 4/20 | 0.59 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CCR2 | P41597 | 3/20 | 0.44 |
| ▸ | PTGES | O14684 | 2/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.43 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.43 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.43 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.43 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3570450 | 0.86 | PLA2G10 (0.79) | ALDH1A1TSHRPLA2G10DAOMCL1 | |
| SCHEMBL30194196 | 0.85 | ALDH1A1 (1.00) | ALDH1A1TSHRPLA2G10DAOMCL1 | |
| SCHEMBL5208338 | 0.85 | ALDH1A1 (1.00) | ALDH1A1TSHRPLA2G10DAOMCL1 | |
| SCHEMBL9149430 | 0.84 | ALDH1A1 (0.79) | ALDH1A1TSHRPLA2G10DAOMCL1 | |
| SCHEMBL13802520 | 0.82 | ALDH1A1 (0.67) | ALDH1A1TSHRPLA2G10DAOMCL1 | |
| SCHEMBL27642609 | 0.82 | KCNH2 (0.48) | ALDH1A1TSHRPLA2G10PPARGPPARA | |
| SCHEMBL3957422 | 0.81 | ALDH1A1 (0.79) | ALDH1A1TSHRPLA2G10DAOMCL1 | |
| SCHEMBL9260948 | 0.81 | ALDH1A1 (0.79) | ALDH1A1TSHRPLA2G10DAOMCL1 | |
| SCHEMBL5421995 | 0.81 | ALDH1A1 (0.79) | ALDH1A1TSHRPLA2G10DAOMCL1 | |
| SCHEMBL5434782 | 0.79 | ALDH1A1 (0.77) | ALDH1A1TSHRPLA2G10DAOMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | APP, PSEN2, PSEN1 | ALDH1A1 2808/4885TSHR 4514/4885PLA2G10 242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.