Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | MRE11 | P49959 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14853427 | 0.87 | EPHX2 (0.68) | EPHX2ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL14850265 | 0.84 | EPHX2 (0.64) | EPHX2ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL3435110 | 0.77 | KDM4E (0.54) | ALDH1A1KDM4ETDP1MEN1KMT2A | |
| SCHEMBL14228908 | 0.76 | EPHX2 (0.55) | EPHX2ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL27494909 | 0.75 | LMNA (0.52) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL10748359 | 0.75 | MAPT (0.72) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL32689500 | 0.74 | KDM4E (0.50) | EPHX2ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL11539713 | 0.74 | CYP2D6 (0.68) | EPHX2ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL6838359 | 0.74 | KMT2A (0.68) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL14055 | 0.73 | CYP2C19 (0.55) | ALDH1A1MEN1MAPTKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011047323-A2 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2011-04-21 | — | — | WO | disclosed |