Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13803 | 0.76 | EPHX2 (0.66) | EPHX2KDM4EALDH1A1TDP1KMT2A | |
| SCHEMBL19034905 | 0.74 | TDP1 (0.61) | ALDH1A1TDP1KMT2AMEN1POLB | |
| SCHEMBL14853427 | 0.73 | EPHX2 (0.68) | EPHX2KDM4EALDH1A1TDP1KMT2A | |
| SCHEMBL14228907 | 0.73 | TDP1 (0.57) | KDM4EALDH1A1TDP1KMT2ATP53 | |
| SCHEMBL5509441 | 0.72 | THRB (0.50) | ALDH1A1TDP1KMT2AMEN1LMNA | |
| SCHEMBL9417499 | 0.71 | PTPN1 (0.54) | ALDH1A1TDP1KMT2AMEN1POLB | |
| SCHEMBL14850265 | 0.71 | EPHX2 (0.64) | EPHX2KDM4EALDH1A1TDP1KMT2A | |
| SCHEMBL5752269 | 0.69 | LTA4H (0.64) | ALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11257115 | 0.69 | SIGMAR1 (0.59) | KDM4EL3MBTL1 | |
| SCHEMBL5516797 | 0.69 | L3MBTL1 (0.56) | KDM4EALDH1A1TDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7354568-B1 | Magnetic resonance imaging agents for the detection of physiological agents | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2008-04-08 | — | — | US | disclosed |