SCHEMBL13803333

SCHEMBL13803333

c1ccc(N(c2ccc(-c3ccc4c(c3)c3ccccc3n4-c3cccc4ccccc34)cc2)c2ccc(-c3cccc4ccccc34)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38
TSPO P30536 3/20 0.37
POLB P06746 1/20 0.36
MCL1 Q07820 1/20 0.34
ACMSD Q8TDX5 1/20 0.34
PPARG P37231 5/20 0.33
PPARA Q07869 5/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TUBB4A P04350 1/20 0.32
TUBB P07437 1/20 0.32
TUBA3C P0DPH7 1/20 0.32
TUBA1B P68363 1/20 0.32
TUBA4A P68366 1/20 0.32
TUBB4B P68371 1/20 0.32
TUBB3 Q13509 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13803632 0.98 CA12 (0.41) CA12CA1CA2CA9TSPO
SCHEMBL13803780 0.98 CA12 (0.40) CA12CA1CA2CA9TSPO
SCHEMBL23078491 0.94 CA12 (0.40) CA12CA1CA2CA9TSPO
SCHEMBL23078297 0.94 CA12 (0.40) CA12CA1CA2CA9TSPO
SCHEMBL16557349 0.94 TSPO (0.40) TSPOPOLBALDH1A1
SCHEMBL19383364 0.94 TSPO (0.40) TSPOPOLBALDH1A1
SCHEMBL16812246 0.93 CA12 (0.37) CA12CA1CA2CA9TSPO
SCHEMBL13803910 0.93 CA12 (0.37) CA12CA1CA2CA9TSPO
SCHEMBL23077969 0.93 CA12 (0.41) CA12CA1CA2CA9TSPO
SCHEMBL23078094 0.93 CA12 (0.41) CA12CA1CA2CA9TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220388958-A1 CARBAZOLE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING CARBAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2022-12-08 US disclosed
US-10556864-B2 Carbazole derivative, and light-emitting element, light-emitting device, and electronic device using the carbazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-02-11 US disclosed
US-20190040009-A1 Carbazole Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Carbazole Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-02-07 US disclosed
US-20180009751-A1 Carbazole Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Carbazole Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-01-11 US disclosed
EP-2757094-A1 Carbazole derivative, and light-emitting element, light-emitting device, and electronic device uing carbazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-07-23 EP disclosed
US-20090160323-A1 Carbazole Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-06-25 US disclosed
WO-2009072587-A1 CARBAZOLE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING CARBAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-06-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10556864-B2 Carbazole derivative, and light-emitting element, light-emitting device, and electronic device using the carbazole derivative NR2E3, CRY1, AHR CA12 4045/4885CA1 3287/4885CA2 2143/4885
US-20190040009-A1 Carbazole Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Carbazole Derivative NR2E3, CRY1, AHR CA12 4045/4885CA1 3287/4885CA2 2143/4885
US-20220388958-A1 CARBAZOLE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING CARBAZOLE DERIVATIVE CRY1, AP3D1, AHR CA12 4115/4885CA1 3297/4885CA2 2161/4885
US-20180009751-A1 Carbazole Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Carbazole Derivative NR2E3, CRY1, AHR CA12 4045/4885CA1 3287/4885CA2 2143/4885
US-20090160323-A1 Carbazole Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative CRY1, AP3D1, AHR CA12 4115/4885CA1 3297/4885CA2 2161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.