Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SELL | P14151 | 2/20 | 0.36 |
| ▸ | SELP | P16109 | 2/20 | 0.36 |
| ▸ | SELE | P16581 | 2/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13804255 | 1.00 | PLG (0.38) | PLGPLATLMNABTKLTA4H | |
| SCHEMBL13804198 | 1.00 | PLG (0.38) | PLGPLATLMNABTKLTA4H | |
| SCHEMBL13804203 | 1.00 | PLG (0.38) | PLGPLATLMNABTKLTA4H | |
| SCHEMBL12997498 | 1.00 | PLG (0.38) | PLGPLATLMNABTKLTA4H | |
| SCHEMBL23525279 | 0.89 | LMNA (0.43) | PLGPLATLMNALTA4HKCNH2 | |
| SCHEMBL10068040 | 0.89 | LMNA (0.43) | PLGPLATLMNALTA4HKCNH2 | |
| SCHEMBL12056723 | 0.89 | LMNA (0.43) | PLGPLATLMNALTA4HKCNH2 | |
| SCHEMBL13073782 | 0.88 | BTK (0.50) | LMNABTKKCNH2S1PR5TSHR | |
| SCHEMBL26452141 | 0.85 | APLNR (0.36) | PLGPLATLMNABTKKCNH2 | |
| SCHEMBL13804163 | 0.82 | SMN1; SMN2 (0.41) | LMNALTA4HKCNH2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070485-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-α]IMIDAZOLE-3- CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-06-04 | — | — | WO | disclosed |