SCHEMBL13805651

SCHEMBL13805651

CCC(=O)NCCOCCOCCOCCOCCC(=O)NCCCC[C@H](C)C(C)=O

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.45
▸ KMT2A Q03164 2/20 0.45
▸ GLP1R P43220 8/20 0.41
▸ CASP2 P42575 1/20 0.36
▸ RECQL P46063 1/20 0.36
▸ TSHR P16473 1/20 0.36
▸ NAAA Q02083 1/20 0.35
▸ FOLH1 Q04609 2/20 0.34
▸ ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL71906 0.90 MEN1 (0.45) MEN1KMT2AGLP1RRECQLTSHR
SCHEMBL71138 0.89 EPHX2 (0.41) GLP1RCASP2TSHR
SCHEMBL13805652 0.85 GLP1R (0.49) MEN1KMT2AGLP1RCASP2RECQL
SCHEMBL16593142 0.84 MEN1 (0.63) MEN1KMT2ACASP2RECQLNAAA
SCHEMBL13805654 0.84 GLP1R (0.53) MEN1KMT2AGLP1RCASP2RECQL
SCHEMBL13805653 0.83 GLP1R (0.57) GLP1RCASP2NAAA
SCHEMBL71147 0.82 GLP1R (0.46) MEN1KMT2AGLP1RCASP2RECQL
SCHEMBL14683467 0.82 GLP1R (0.44) MEN1KMT2AGLP1RRECQLTSHR
SCHEMBL14683527 0.82 GLP1R (0.44) MEN1KMT2AGLP1RTSHRALDH1A1
SCHEMBL71315 0.82 GLP1R (0.46) MEN1KMT2AGLP1RCASP2RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090156478-A1 Acylated GLP-1 Compounds NOVO NORDISK A/S (DK) 2009-06-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156478-A1 Acylated GLP-1 Compounds GLP1R, GIPR, GCGR MEN1 922/4885KMT2A 2972/4885GLP1R 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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