Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
| ▸ | GLP1R | P43220 | 8/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13805651 | 0.89 | MEN1 (0.45) | TSHRCASP2GLP1R | |
| SCHEMBL14683527 | 0.86 | GLP1R (0.44) | EPHX2TSHRGLP1RRAB9A | |
| SCHEMBL14683467 | 0.84 | GLP1R (0.44) | EPHX2TSHRGLP1R | |
| SCHEMBL15357462 | 0.82 | NAMPT (0.44) | TSHRCASP2GLP1RRAB9A | |
| SCHEMBL14683581 | 0.82 | ALDH1A1 (0.40) | EPHX2TSHRGLP1RRAB9A | |
| SCHEMBL13805652 | 0.82 | GLP1R (0.49) | TSHRCASP2GLP1R | |
| SCHEMBL13805654 | 0.81 | GLP1R (0.53) | TSHRCASP2GLP1R | |
| SCHEMBL14683575 | 0.81 | FAAH (0.43) | EPHX2TSHRCASP2GLP1R | |
| SCHEMBL13147071 | 0.80 | GLP1R (0.55) | GLP1R | |
| SCHEMBL13147048 | 0.80 | GLP1R (0.55) | GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129343-B2 | Acylated GLP-1 compounds | NOVO NORDISK A/S (DK) | 2012-03-06 | — | — | US | disclosed |
| US-20090156478-A1 | Acylated GLP-1 Compounds | NOVO NORDISK A/S (DK) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156478-A1 | Acylated GLP-1 Compounds | GLP1R, GIPR, GCGR | EPHX2 4514/4885SMN1; SMN2 2903/4885TSHR 525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.