Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 18/20 | 0.41 |
| ▸ | RAMP1 | O60894 | 7/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4079721 | 0.83 | PDE3B (0.41) | CALCRLRAMP1 | |
| SCHEMBL21900259 | 0.83 | CALCRL (0.40) | CALCRLRAMP1CRBN | |
| SCHEMBL2087424 | 0.83 | CALCRL (0.55) | CALCRLRAMP1CHRM4 | |
| SCHEMBL3593027 | 0.76 | CALCRL (0.43) | CALCRLRAMP1CYP3A4CHRM4 | |
| SCHEMBL30231301 | 0.74 | CALCRL (0.58) | CALCRLRAMP1CHRM4 | |
| SCHEMBL2103739 | 0.74 | CALCRL (0.58) | CALCRLRAMP1CHRM4 | |
| SCHEMBL27689313 | 0.73 | CDA (0.38) | CALCRLRAMP1CHRM4CRBN | |
| SCHEMBL17881547 | 0.72 | KDM4E (0.49) | CRBN | |
| SCHEMBL3599617 | 0.72 | TNKS (0.55) | CALCRLRAMP1CYP3A4CHRM4 | |
| SCHEMBL13655717 | 0.72 | CALCRL (0.52) | CALCRLRAMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2065382-A1 | CGRP antagonists | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2009-06-03 | — | — | EP | disclosed |