Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 18/20 | 0.40 |
| ▸ | RAMP1 | O60894 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30178430 | 0.86 | GPR119 (0.49) | CALCRLRAMP1CRBN | |
| SCHEMBL17881255 | 0.84 | MAPK1 (0.39) | CALCRLUSP2 | |
| SCHEMBL13806416 | 0.83 | CALCRL (0.41) | CALCRLRAMP1CRBN | |
| SCHEMBL19873973 | 0.83 | HTR2A (0.39) | CALCRLRAMP1USP2 | |
| SCHEMBL4079721 | 0.82 | PDE3B (0.41) | CALCRLRAMP1 | |
| SCHEMBL2087424 | 0.80 | CALCRL (0.55) | CALCRLRAMP1 | |
| SCHEMBL3593027 | 0.73 | CALCRL (0.43) | CALCRLRAMP1 | |
| SCHEMBL13655717 | 0.72 | CALCRL (0.52) | CALCRLRAMP1 | |
| SCHEMBL30231301 | 0.71 | CALCRL (0.58) | CALCRLRAMP1 | |
| SCHEMBL2103739 | 0.71 | CALCRL (0.58) | CALCRLRAMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3708566-B1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2023-02-08 | — | — | EP | disclosed |
| EP-3708566-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2020-09-16 | — | — | EP | disclosed |
| EP-3237403-B1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2020-05-06 | — | — | EP | disclosed |