Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | SELP | P16109 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19646651 | 0.85 | ALDH1A1 (0.34) | ALDH1A1MEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL24641589 | 0.81 | SMN1; SMN2 (0.37) | ALDH1A1MEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL13807014 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL24478833 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL21964558 | 0.80 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AFAAHTP53 | |
| SCHEMBL8477259 | 0.80 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AFAAHTP53 | |
| SCHEMBL14184587 | 0.80 | MCL1 (0.38) | KMT2ARAB9AFAAHSMN1; SMN2 | |
| SCHEMBL12085207 | 0.79 | CASP2 (0.53) | MEN1KMT2AFAAHNAAA | |
| SCHEMBL22680198 | 0.79 | CASP2 (0.53) | MEN1KMT2AFAAHNAAA | |
| SCHEMBL12642026 | 0.79 | CASP2 (0.53) | MEN1KMT2AFAAHNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009074569-A1 | TARGETING AND THERAPEUTIC COMPOUNDS WITH A POLYPROLINE-COMPRISING SPACER AND GAS-FILLED MICROVESICLES COMPRISING SAID COMPOUNDS | BRACCO INTERNATIONAL BV (NL) | 2009-06-18 | — | — | WO | disclosed |