Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1379285 | 0.79 | KMT2A (0.42) | TDP1KMT2A | |
| SCHEMBL27980649 | 0.72 | OPRD1 (0.44) | OPRD1KMT2A | |
| SCHEMBL1381034 | 0.69 | KCNH2 (0.46) | — | |
| SCHEMBL5585868 | 0.69 | POLB (0.41) | KMT2A | |
| SCHEMBL6189155 | 0.69 | MEN1 (0.50) | KMT2A | |
| SCHEMBL16598721 | 0.66 | DPP4 (0.42) | OPRD1KMT2A | |
| SCHEMBL7860425 | 0.66 | TACR1 (0.50) | KMT2A | |
| SCHEMBL6185432 | 0.64 | POLB (0.37) | KMT2A | |
| SCHEMBL4575056 | 0.64 | KMT2A (0.42) | TDP1KMT2A | |
| SCHEMBL1819575 | 0.63 | SLC1A2 (0.43) | OPRD1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4825664-B2 | — | — | 2011-11-30 | — | — | JP | claimed |
| EP-1592389-A2 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | Applied Research Systems ARS Holding N.V. (AN) | 2005-11-09 | — | — | EP | claimed |
| WO-2004071390-A2 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2004-08-26 | — | — | WO | claimed |