Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4003863 | 0.94 | PABPC1 (0.39) | KMT2AMAPTNPC1RAB9APSMD14 | |
| SCHEMBL13808911 | 0.94 | PABPC1 (0.39) | KMT2AMAPTNPC1RAB9APSMD14 | |
| SCHEMBL13808905 | 0.89 | PABPC1 (0.36) | KMT2AMAPTNPC1RAB9APSMD14 | |
| SCHEMBL4007335 | 0.89 | PABPC1 (0.36) | KMT2AMAPTNPC1RAB9APSMD14 | |
| SCHEMBL13808757 | 0.83 | KDM4E (0.33) | KMT2ANPC1RAB9AMEN1GAA | |
| SCHEMBL13808756 | 0.83 | PABPC1 (0.34) | MAPTPABPC1TP53CYP3A4CASP1 | |
| SCHEMBL4010569 | 0.82 | TP53 (0.36) | MAPTGAAKDM4EPABPC1ALDH1A1 | |
| SCHEMBL4010574 | 0.82 | TP53 (0.36) | MAPTGAAKDM4EPABPC1ALDH1A1 | |
| SCHEMBL12997465 | 0.81 | KCNH2 (0.34) | KMT2AMAPTPABPC1ALDH1A1THRB | |
| SCHEMBL4001393 | 0.81 | TP53 (0.36) | MAPTPABPC1TP53CYP3A4CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009077394-A1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF THESE DYES OBTAINED FROM 5-(2-HYDROXYETHYLAMINO)-2-METHYLPHENOL, AND DYEING PROCESS USING THESE DYES AND PRECURSORS | L'OREAL (FR) | 2009-06-25 | — | — | WO | disclosed |