Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.31 |
| ▸ | MEN1 | O00255 | 4/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LHCGR | P22888 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12811829 | 0.86 | EPHX1 (0.42) | ALDH1A1RAB9AEPHX1KMT2AMEN1 | |
| SCHEMBL2676319 | 0.85 | EPHX1 (0.49) | ALDH1A1RAB9AEPHX1KMT2ASMN1; SMN2 | |
| SCHEMBL13547213 | 0.85 | EPHX1 (0.49) | ALDH1A1RAB9AEPHX1KMT2ASMN1; SMN2 | |
| SCHEMBL12995653 | 0.81 | DRD2 (0.46) | GAAEPHX1KMT2ADRD2 | |
| SCHEMBL13547356 | 0.80 | HTT (0.38) | ALDH1A1RAB9AMGLLEPHX1TSHR | |
| SCHEMBL3612641 | 0.78 | HTT (0.36) | ALDH1A1RAB9AEPHX1SMN1; SMN2POLB | |
| SCHEMBL3617697 | 0.78 | HTT (0.36) | ALDH1A1RAB9AEPHX1SMN1; SMN2POLB | |
| SCHEMBL13547230 | 0.77 | KDM4E (0.33) | GAAEPHX1POLB | |
| SCHEMBL13547228 | 0.77 | KDM4E (0.33) | GAAEPHX1POLB | |
| SCHEMBL13547377 | 0.76 | KDM4E (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009071638-A2 | PROCESS FOR THE PREPARATION OF 2-(PRIMARY/SECONDARY AMINO)HYDROCARBYL)- CARBAMOYL-7-OXO-2,6-DIAZA-BICYCLO[3.2.0.]HEPTANE-6-SULFONIC ACID DERIVATIVES | BASILEA PHARMACEUTICA AG (CH) | 2009-06-11 | — | — | WO | disclosed |