SCHEMBL13809185

SCHEMBL13809185

COc1ccc2ccc3c(c2c1)N=CC1(O3)N(C)c2ccc3ccccc3c2C1(C)C

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.75
THRB P10828 5/20 0.75
KDM4E B2RXH2 5/20 0.75
SMN1; SMN2 Q16637 4/20 0.75
ALDH1A1 P00352 3/20 0.75
HPGD P15428 3/20 0.75
HTT P42858 3/20 0.75
L3MBTL1 Q9Y468 3/20 0.75
LMNA P02545 3/20 0.75
ALOX12 P18054 2/20 0.75
GAA P10253 2/20 0.75
RECQL P46063 2/20 0.75
TDP1 Q9NUW8 2/20 0.75
POLB P06746 1/20 0.75
MAPK1 P28482 1/20 0.75
PKM P14618 2/20 0.60
NPSR1 Q6W5P4 8/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21916975 0.89 MAPT (0.75) MAPTTHRBKDM4ESMN1; SMN2ALDH1A1
SCHEMBL11071776 0.87 MAPT (0.68) MAPTTHRBKDM4ESMN1; SMN2ALDH1A1
SCHEMBL23800871 0.87 MAPT (0.61) MAPTTHRBKDM4ESMN1; SMN2ALDH1A1
SCHEMBL9996010 0.87 MAPT (0.80) MAPTTHRBKDM4ESMN1; SMN2ALDH1A1
SCHEMBL4620516 0.86 MAPT (1.00) MAPTTHRBKDM4ESMN1; SMN2ALDH1A1
SCHEMBL9839799 0.85 MAPT (0.55) MAPTTHRBKDM4ESMN1; SMN2ALDH1A1
SCHEMBL14077721 0.85 MAPT (0.56) MAPTTHRBKDM4ESMN1; SMN2ALDH1A1
SCHEMBL7091457 0.85 MAPT (0.70) MAPTTHRBKDM4ESMN1; SMN2ALDH1A1
SCHEMBL9325279 0.84 MAPT (0.79) MAPTTHRBKDM4ESMN1; SMN2ALDH1A1
SCHEMBL23800863 0.84 MAPT (0.57) MAPTTHRBKDM4ESMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1754614-B1 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORP (JP) 2009-06-17 EP disclosed
US-7524605-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2009-04-28 US disclosed
US-7524605-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2009-04-28 US disclosed
US-20070082291-A1 Lithographic Printing Plate Precursor and Lithographic Printing Method FUJI PHOTO FILM CO., LTD. (JP) 2007-04-12 US disclosed
EP-1754614-A1 Lithographic printing plate precursor and lithographic printing method Fuji Photo Film Co., Ltd. (JP) 2007-02-21 EP disclosed