SCHEMBL9839799

SCHEMBL9839799

COc1cc(OC)c2c(c1)OC1(C=N2)N(C)c2ccc3ccccc3c2C1(C)C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.55
KDM4E B2RXH2 4/20 0.55
THRB P10828 4/20 0.55
SMN1; SMN2 Q16637 3/20 0.55
HTT P42858 3/20 0.55
LMNA P02545 3/20 0.55
ALDH1A1 P00352 2/20 0.55
HPGD P15428 2/20 0.55
ALOX12 P18054 2/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
GAA P10253 1/20 0.55
POLB P06746 1/20 0.55
MAPK1 P28482 1/20 0.55
RECQL P46063 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
PKM P14618 1/20 0.52
NPSR1 Q6W5P4 2/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13809185 0.85 MAPT (0.75) MAPTKDM4ETHRBSMN1; SMN2HTT
SCHEMBL21916975 0.81 MAPT (0.75) MAPTKDM4ETHRBSMN1; SMN2HTT
SCHEMBL14077718 0.81 KDM4E (0.59) MAPTKDM4ETHRBSMN1; SMN2HTT
SCHEMBL9226446 0.80 MAPT (0.58) MAPTKDM4ETHRBSMN1; SMN2HTT
SCHEMBL14077727 0.79 KDM4E (0.54) MAPTKDM4ETHRBSMN1; SMN2HTT
SCHEMBL14077721 0.79 MAPT (0.56) MAPTKDM4ETHRBSMN1; SMN2HTT
SCHEMBL10428638 0.77 MAPT (0.51) MAPTKDM4ETHRBSMN1; SMN2HTT
SCHEMBL9996010 0.77 MAPT (0.80) MAPTKDM4ETHRBSMN1; SMN2HTT
SCHEMBL16313236 0.76 MAPT (0.36) MAPTKDM4ETHRBSMN1; SMN2HTT
SCHEMBL17342543 0.76 KDM4E (0.61) MAPTKDM4ETHRBSMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1754614-B1 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORP (JP) 2009-06-17 EP disclosed
US-7524605-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2009-04-28 US disclosed
US-7524605-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2009-04-28 US disclosed
US-20070082291-A1 Lithographic Printing Plate Precursor and Lithographic Printing Method FUJI PHOTO FILM CO., LTD. (JP) 2007-04-12 US disclosed
EP-0417128-A1 PHOTOCHROMIC COMPOUND AND ARTICLES CONTAINING THE SAME PPG INDUSTRIES, INC. (US) 1991-03-20 EP disclosed
US-4936995-A SPIRO(BENZINDOLINO) BENZOXAZINE COMPOUNDS PPG INDUSTRIES, INC. (US) 1990-06-26 US disclosed
WO-1989011482-A1 PHOTOCHROMIC COMPOUND AND ARTICLES CONTAINING THE SAME PPG INDUSTRIES, INC. (US) 1989-11-30 WO disclosed