SCHEMBL9996010

SCHEMBL9996010

COc1ccc2c(c1)C(C)(C)C1(C=Nc3c(ccc4ccccc34)O1)N2C

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.80
KDM4E B2RXH2 7/20 0.80
THRB P10828 5/20 0.80
LMNA P02545 5/20 0.80
GAA P10253 5/20 0.80
SMN1; SMN2 Q16637 4/20 0.80
ALDH1A1 P00352 4/20 0.80
HPGD P15428 4/20 0.80
HTT P42858 3/20 0.80
L3MBTL1 Q9Y468 3/20 0.80
RECQL P46063 3/20 0.80
TDP1 Q9NUW8 3/20 0.80
ALOX12 P18054 2/20 0.80
MAPK1 P28482 2/20 0.80
POLB P06746 1/20 0.80
PKM P14618 2/20 0.74
NPSR1 Q6W5P4 4/20 0.49
CYP3A4 P08684 2/20 0.49
CYP2C9 P11712 2/20 0.49
CYP2C19 P33261 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12347548 0.94 MAPT (0.71) MAPTKDM4ETHRBLMNAGAA
SCHEMBL4620516 0.89 MAPT (1.00) MAPTKDM4ETHRBLMNAGAA
SCHEMBL6481062 0.89 MAPT (0.68) MAPTKDM4ETHRBLMNAGAA
SCHEMBL3439122 0.88 MAPT (0.74) MAPTKDM4ETHRBLMNAGAA
SCHEMBL9867611 0.87 MAPT (0.70) MAPTKDM4ETHRBLMNAGAA
SCHEMBL3158374 0.87 MAPT (0.67) MAPTKDM4ETHRBLMNAGAA
SCHEMBL13809185 0.87 MAPT (0.75) MAPTKDM4ETHRBLMNAGAA
SCHEMBL4621970 0.87 MAPT (0.79) MAPTKDM4ETHRBLMNAGAA
SCHEMBL27570192 0.87 MAPT (0.61) MAPTKDM4ETHRBLMNAGAA
SCHEMBL4620865 0.87 MAPT (0.78) MAPTKDM4ETHRBLMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4440672-A SPIRO(INDOLINE-2,3'-(3'H)-NAPHTN(1,2-B)(1,4) OXAZINES), ULTRAVIOLET STABILIZER AMERICAN OPTICAL CORPORATION (US) 1984-04-03 US claimed
US-11543750-B2 Lithographic printing plate precursor and method for producing lithographic printing plate FUJIFILM CORPORATION (JP) 2023-01-03 US disclosed
US-20200117086-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD FOR PRODUCING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2020-04-16 US disclosed
US-10249693-B2 Organic light-emitting display apparatus SAMSUNG DISPLAY CO., LTD. (KR) 2019-04-02 US disclosed
US-20140231780-A1 ORGANIC LIGHT-EMITTING DISPLAY APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2014-08-21 US disclosed
US-8729793-B2 Organic light-emitting display apparatus SAMSUNG DISPLAY CO., LTD. (KR) 2014-05-20 US disclosed
US-8508121-B2 Organic light-emitting display apparatus SAMSUNG DISPLAY CO., LTD. (KR) 2013-08-13 US disclosed
US-20110291552-A1 ORGANIC LIGHT-EMITTING DISPLAY APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2011-12-01 US disclosed
US-4756973-A Three-dimensional network structure layer forming resin containing spirooxazine compound and phenolic resin KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-07-12 US disclosed