Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 9/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 4/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.42 |
| ▸ | NOS2 | P35228 | 2/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13809203 | 0.86 | ESR1 (0.43) | TAAR1ALDH1A1SLC6A2BLMTDP1 | |
| SCHEMBL12309927 | 0.80 | ESR1 (0.61) | SLC6A2BLMKMT2AESR1 | |
| SCHEMBL15443987 | 0.79 | ESR1 (0.43) | TAAR1ALDH1A1L3MBTL1BLMKMT2A | |
| SCHEMBL13078449 | 0.79 | ESR1 (0.43) | TAAR1KDM4EALDH1A1L3MBTL1BLM | |
| SCHEMBL15457714 | 0.79 | ESR1 (0.43) | SLC6A2BLMHTR2ANOS3NOS1 | |
| SCHEMBL13363663 | 0.78 | GFER (0.46) | ALDH1A1TDP1LOXL2SMN1; SMN2MAOB | |
| SCHEMBL15443986 | 0.77 | ESR1 (0.42) | BLMCYP1A2ESR1 | |
| SCHEMBL12224660 | 0.77 | ESR1 (0.42) | ALDH1A1SLC6A2BLMHTR2AESR1 | |
| SCHEMBL881459 | 0.77 | ESR1 (0.42) | TAAR1KDM4EALDH1A1BLMHTR2A | |
| SCHEMBL18608262 | 0.76 | SLC6A2 (0.50) | TAAR1ALDH1A1SLC6A2CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009076618-A2 | GENERATION OF COMBINATORIAL SYNTHETIC LIBRARIES AND SCREENING FOR NOVEL PROADHESINS AND NONADHESINS | CERNOFINA, LLC (US) | 2009-06-18 | — | — | WO | disclosed |
| US-20090124690-A1 | Generation of Combinatorial Synthetic Libraries and Screening for Novel Proadhesins and Nonadhesins | CERNOFINA, LLC | 2009-05-14 | — | — | US | disclosed |
| US-7479571-B2 | Generation of combinatorial synthetic libraries and screening for novel proadhesins and nonadhesins | CERNOFINA, LLC (US) | 2009-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124690-A1 | Generation of Combinatorial Synthetic Libraries and Screening for Novel Proadhesins and Nonadhesins | SELP, SELE, SELPLG | TAAR1 1904/4885KDM4E 4627/4885ALDH1A1 1723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.