Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2C | Q14957 | 9/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13809251 | 0.82 | GRIN2C (0.49) | GRIN2CMTNR1BMEN1KMT2AFKBP1A | |
| SCHEMBL4423041 | 0.74 | GRIN2C (0.54) | GRIN2CMTNR1BMEN1KMT2A | |
| SCHEMBL13809019 | 0.73 | GRIN2C (0.44) | GRIN2CMTNR1BMEN1KMT2AFKBP1A | |
| SCHEMBL13809246 | 0.73 | GRIN2C (0.51) | GRIN2CMEN1KMT2A | |
| SCHEMBL4411732 | 0.72 | GRIN2C (0.56) | GRIN2CGRIN2DMEN1KMT2A | |
| SCHEMBL4423047 | 0.72 | GRIN2C (0.51) | GRIN2CMTNR1BMEN1KMT2A | |
| SCHEMBL4412003 | 0.72 | GRIN2C (0.55) | GRIN2CGRIN2DMEN1KMT2A | |
| SCHEMBL13809247 | 0.72 | GRIN2C (0.49) | GRIN2CGRIN2DMEN1KMT2A | |
| SCHEMBL4414956 | 0.71 | GRIN2C (0.54) | GRIN2CGRIN2DMEN1KMT2A | |
| SCHEMBL4422268 | 0.71 | GRIN2C (0.55) | GRIN2CGRIN2DMTNR1BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009073545-A2 | TETRAHYDRO-ISOQUINOLINE PPAT INHIBITORS AS ANTIBACTERIAL AGENTS | MAXTHERA, INC. (US) | 2009-06-11 | — | — | WO | disclosed |