Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2C | Q14957 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13809245 | 0.86 | RXFP1 (0.45) | GRIN2CKMT2AMEN1TP53LMNA | |
| SCHEMBL13809247 | 0.83 | GRIN2C (0.49) | GRIN2CKMT2AMEN1TP53LMNA | |
| SCHEMBL13809227 | 0.82 | GRIN2C (0.43) | GRIN2CKMT2AMEN1TP53LMNA | |
| SCHEMBL13809019 | 0.80 | GRIN2C (0.44) | GRIN2CKMT2AMEN1TP53LMNA | |
| SCHEMBL13809233 | 0.78 | GRIN2C (0.43) | GRIN2CKMT2AMEN1LMNA | |
| SCHEMBL4413383 | 0.73 | KMT2A (0.47) | GRIN2CKMT2AMEN1TP53LMNA | |
| SCHEMBL13809240 | 0.73 | GRIN2C (0.54) | GRIN2CKMT2AMEN1 | |
| SCHEMBL4414980 | 0.72 | KMT2A (0.60) | GRIN2CKMT2AMEN1TP53LMNA | |
| SCHEMBL4552564 | 0.72 | GRIN2C (0.64) | GRIN2CKMT2AMEN1TP53LMNA | |
| SCHEMBL4423041 | 0.72 | GRIN2C (0.54) | GRIN2CKMT2AMEN1TP53CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009073545-A2 | TETRAHYDRO-ISOQUINOLINE PPAT INHIBITORS AS ANTIBACTERIAL AGENTS | MAXTHERA, INC. (US) | 2009-06-11 | — | — | WO | disclosed |