Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13592119 | 0.89 | LMNA (0.54) | ALDH1A1MEN1KMT2APKMLMNA | |
| SCHEMBL14093631 | 0.87 | KMT2A (0.48) | ALDH1A1MEN1KMT2APKMCCR6 | |
| SCHEMBL14093356 | 0.79 | KMT2A (0.51) | ALDH1A1MEN1KMT2APKMLMNA | |
| SCHEMBL13592187 | 0.77 | PKM (0.52) | ALDH1A1MEN1KMT2APKMCCR6 | |
| SCHEMBL13592095 | 0.77 | POLB (0.57) | ALDH1A1MEN1KMT2APKML3MBTL1 | |
| SCHEMBL13809326 | 0.77 | PKM (0.57) | ALDH1A1MEN1KMT2APKMCCR6 | |
| SCHEMBL13592106 | 0.77 | PKM (0.57) | ALDH1A1MEN1KMT2APKMCCR6 | |
| SCHEMBL13592100 | 0.76 | CNR1 (0.54) | ALDH1A1MEN1KMT2APKMLMNA | |
| SCHEMBL14093622 | 0.76 | PKM (0.53) | ALDH1A1KMT2APKMCCR6 | |
| SCHEMBL13809460 | 0.76 | PKM (0.50) | ALDH1A1MEN1KMT2APKMCCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660131-B1 | ACTIVE SUBSTANCE COMBINATION COMPRISING A COMPOUND WITH NPY RECEPTOR AFFINITY AND A COMPOUND WITH 5-HT6 RECEPTOR AFFINITY | ESTEVE LABOR DR (ES) | 2009-06-24 | — | — | EP | disclosed |