Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MIF | P14174 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HK1 | P19367 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1119804 | 0.92 | ALDH1A1 (0.42) | SMN1; SMN2LMNAHTTALDH1A1TSHR | |
| SCHEMBL1119889 | 0.90 | CCR2 (0.36) | ALDH1A1TSHR | |
| SCHEMBL15353817 | 0.88 | KCNJ1 (0.32) | SMN1; SMN2LMNAHTTALDH1A1TSHR | |
| SCHEMBL15353818 | 0.88 | KCNJ1 (0.32) | SMN1; SMN2LMNAHTTALDH1A1TSHR | |
| SCHEMBL15353819 | 0.88 | KCNJ1 (0.32) | SMN1; SMN2LMNAHTTALDH1A1TSHR | |
| SCHEMBL13043949 | 0.83 | CCR2 (0.35) | — | |
| SCHEMBL13011667 | 0.82 | CCR2 (0.39) | — | |
| SCHEMBL1120068 | 0.82 | CCR2 (0.39) | — | |
| SCHEMBL13011668 | 0.82 | CCR2 (0.39) | — | |
| SCHEMBL1119752 | 0.82 | CYP3A4 (0.35) | SMN1; SMN2ALDH1A1TSHRMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009076512-A1 | CARBOXAMIDΞ COMPOUNDS AND THEIR USE AS CHEMOKINE RECEPTOR AGONISTS | EPIX DELAWARE, INC. (US) | 2009-06-18 | — | — | WO | disclosed |