Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13809767 | 1.00 | SMN1; SMN2 (0.36) | SMN1; SMN2GAAMCHR1KCNH2MCHR2 | |
| SCHEMBL3735950 | 0.90 | CCR2 (0.42) | KCNH2CCR2 | |
| SCHEMBL1119890 | 0.90 | CCR2 (0.42) | KCNH2CCR2 | |
| SCHEMBL3742106 | 0.90 | CCR2 (0.42) | KCNH2CCR2 | |
| SCHEMBL13074493 | 0.89 | MCHR1 (0.33) | MCHR1KCNH2MCHR2NAMPTSSTR5 | |
| SCHEMBL13074492 | 0.89 | MCHR1 (0.33) | MCHR1KCNH2MCHR2NAMPTSSTR5 | |
| SCHEMBL1120051 | 0.85 | CCR2 (0.41) | KCNH2CCR2 | |
| SCHEMBL1119838 | 0.83 | CCR2 (0.42) | KCNH2CCR2 | |
| SCHEMBL1119805 | 0.80 | CCR2 (0.39) | KCNH2CCR2 | |
| SCHEMBL1119826 | 0.80 | CCR2 (0.39) | KCNH2CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009076512-A1 | CARBOXAMIDΞ COMPOUNDS AND THEIR USE AS CHEMOKINE RECEPTOR AGONISTS | EPIX DELAWARE, INC. (US) | 2009-06-18 | — | — | WO | disclosed |