Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13819365 | 1.00 | TSHR (0.48) | TSHRALDH1A1TP53CYP3A4SMN1; SMN2 | |
| SCHEMBL13810494 | 1.00 | TSHR (0.48) | TSHRALDH1A1TP53CYP3A4SMN1; SMN2 | |
| SCHEMBL13085576 | 1.00 | TSHR (0.48) | TSHRALDH1A1TP53CYP3A4SMN1; SMN2 | |
| SCHEMBL4558827 | 1.00 | TSHR (0.48) | TSHRALDH1A1TP53CYP3A4SMN1; SMN2 | |
| SCHEMBL2866318 | 0.88 | ALDH1A1 (0.51) | TSHRALDH1A1TP53CYP3A4SMN1; SMN2 | |
| SCHEMBL4558998 | 0.87 | PPARG (0.42) | TSHRALDH1A1TP53HIF1ATDP1 | |
| SCHEMBL14309181 | 0.84 | TSHR (0.52) | TSHRALDH1A1TP53CYP3A4SMN1; SMN2 | |
| SCHEMBL13091916 | 0.81 | ALDH1A1 (0.59) | TSHRALDH1A1TP53CYP3A4SMN1; SMN2 | |
| SCHEMBL13810945 | 0.79 | L3MBTL1 (0.44) | TSHRALDH1A1TP53MAPK1L3MBTL1 | |
| SCHEMBL4339926 | 0.79 | MAPK1 (0.46) | TSHRALDH1A1MAPK1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |