⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28746089 | 0.78 | — | — | |
| SCHEMBL15779797 | 0.74 | — | — | |
| SCHEMBL13824463 | 0.71 | — | — | |
| SCHEMBL25608674 | 0.71 | — | — | |
| SCHEMBL22042116 | 0.69 | SIGMAR1 (0.40) | — | |
| SCHEMBL22042117 | 0.69 | SIGMAR1 (0.40) | — | |
| SCHEMBL22042134 | 0.69 | SIGMAR1 (0.40) | — | |
| SCHEMBL13810690 | 0.67 | LTA4H (0.33) | — | |
| SCHEMBL13810692 | 0.67 | MAPT (0.39) | — | |
| SCHEMBL13810689 | 0.67 | MAPT (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541375-B2 | Azole derivatives and pharmaceutical compositions containing them | LABORATOIRES SERONO SA (CH) | 2009-06-02 | — | — | US | disclosed |
| US-20070293555-A1 | AZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2007-12-20 | — | — | US | disclosed |