SCHEMBL13811827

SCHEMBL13811827

CCCCC(C)CN(C)CCC

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GGPS1 O95749 3/20 0.36
LMNA P02545 1/20 0.33
PLA2G1B P04054 1/20 0.32
PLA2G2A P14555 1/20 0.32
DNM1 Q05193 5/20 0.32
ACE2 Q9BYF1 1/20 0.31
PIK3CD O00329 1/20 0.31
OPRM1 P35372 1/20 0.31
CA1 P00915 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12663272 0.93 PLA2G1B (0.39) GGPS1LMNAPLA2G1BPLA2G2ADNM1
SCHEMBL24849421 0.91 PLA2G1B (0.42) GGPS1LMNAPLA2G1BPLA2G2ADNM1
SCHEMBL19752131 0.91 GGPS1 (0.40) GGPS1LMNAPLA2G1BPLA2G2ADNM1
SCHEMBL5949041 0.88 LMNA (0.38) GGPS1LMNAPLA2G1BPLA2G2ADNM1
SCHEMBL29306455 0.87 LMNA (0.41) GGPS1LMNAPLA2G1BPLA2G2ADNM1
SCHEMBL21143018 0.87 GGPS1 (0.50) GGPS1LMNAPLA2G1BPLA2G2ADNM1
SCHEMBL19293362 0.86 TSHR (0.40) GGPS1PIK3CD
SCHEMBL19264421 0.85 GGPS1 (0.44) GGPS1DNM1
SCHEMBL5949352 0.84 LMNA (0.35) LMNAPLA2G1BPLA2G2ADNM1ACE2
SCHEMBL20032034 0.84 OPRM1 (0.45) GGPS1PLA2G1BPLA2G2AOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4241772-A2 PROCESS FOR THE PREPARATION OF COMPOUNDS USEFUL FOR TREATING SPINAL MUSCULAR ATROPHY F. Hoffmann-La Roche AG (CH) 2023-09-13 EP disclosed
US-9593243-B2 Compound, pigment dispersing agent, pigment composition, pigment dispersion and toner containing said compound CANON KABUSHIKI KAISHA (JP) 2017-03-14 US disclosed
EP-1648446-B1 INDOL-4 SULFONAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE 5-HT-6 AS MODULATORS ESTEVE LABOR DR (ES) 2009-06-03 EP disclosed