SCHEMBL13811868

CC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)NC(CC(N)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(N)=O

nearest known ligand 0.60

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	TFPI	P10646	1/20	0.60

▸	OPRL1	P41146	5/20	0.54

▸	KEAP1	Q14145	1/20	0.52

▸	QRFPR	Q96P65	2/20	0.51

▸	IL23R	Q5VWK5	5/20	0.51

▸	KISS1R	Q969F8	1/20	0.49

▸	FURIN	P09958	1/20	0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL10747193	0.88	OPRL1 (0.55)	TFPIOPRL1QRFPRKISS1R
SCHEMBL10747201	0.88	OPRL1 (0.55)	TFPIOPRL1QRFPRKISS1R
SCHEMBL4399651	0.87	OPRL1 (0.54)	TFPIOPRL1KISS1R
SCHEMBL4399655	0.87	OPRL1 (0.54)	TFPIOPRL1KISS1R
SCHEMBL29466809	0.86	TFPI (0.70)	TFPIOPRL1
SCHEMBL29466813	0.86	TFPI (0.70)	TFPIOPRL1
SCHEMBL10744155	0.84	OPRL1 (0.55)	TFPIOPRL1QRFPRKISS1R
SCHEMBL10744135	0.84	OPRL1 (0.55)	TFPIOPRL1QRFPRKISS1R
SCHEMBL24158507	0.83	ITGB3 (0.46)	TFPIIL23R
SCHEMBL24179817	0.83	TFPI (0.51)	TFPIOPRL1KISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-7553809-B2	Fc receptor modulators and uses thereof	ILEXUS PTY LIMITED (AU)	2009-06-30	—	—	US	disclosed