Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 7/20 | 0.55 |
| ▸ | P2RX1 | P51575 | 10/20 | 0.51 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | FADS1 | O60427 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812555 | 0.89 | TMPRSS4 (0.54) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL13812609 | 0.84 | TMPRSS4 (0.64) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL13812699 | 0.84 | MEN1 (0.50) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL13812704 | 0.83 | MEN1 (0.49) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL3863657 | 0.82 | P2RX1 (0.62) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL13812627 | 0.82 | MEN1 (0.55) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL3861646 | 0.82 | KCNMA1 (0.56) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL13812701 | 0.82 | KCNMA1 (0.53) | TMPRSS4P2RX1MEN1KMT2AALOX15 | |
| SCHEMBL13812598 | 0.82 | KCNMA1 (0.51) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL13812587 | 0.82 | MAPT (0.56) | TMPRSS4P2RX1MEN1KMT2AFADS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |